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Synchrotron X‐Ray Fluorescence Nanoprobe Reveals Target Sites for Organo‐Osmium Complex in Human Ovarian Cancer Cells

A variety of transition metal complexes exhibit anticancer activity, but their target sites in cells need to be identified and mechanisms of action elucidated. Here, it was found that the sub‐cellular distribution of [Os(η(6)‐p‐cym)(Azpy‐NMe(2))I](+) (p‐cym=p‐cymene, Azpy‐NMe(2)=2‐(p‐[dimethylamino]...

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Detalles Bibliográficos
Autores principales: Sanchez‐Cano, Carlos, Romero‐Canelón, Isolda, Yang, Yang, Hands‐Portman, Ian J., Bohic, Sylvain, Cloetens, Peter, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412901/
https://www.ncbi.nlm.nih.gov/pubmed/28012260
http://dx.doi.org/10.1002/chem.201605911