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Synchrotron X‐Ray Fluorescence Nanoprobe Reveals Target Sites for Organo‐Osmium Complex in Human Ovarian Cancer Cells
A variety of transition metal complexes exhibit anticancer activity, but their target sites in cells need to be identified and mechanisms of action elucidated. Here, it was found that the sub‐cellular distribution of [Os(η(6)‐p‐cym)(Azpy‐NMe(2))I](+) (p‐cym=p‐cymene, Azpy‐NMe(2)=2‐(p‐[dimethylamino]...
Autores principales: | Sanchez‐Cano, Carlos, Romero‐Canelón, Isolda, Yang, Yang, Hands‐Portman, Ian J., Bohic, Sylvain, Cloetens, Peter, Sadler, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412901/ https://www.ncbi.nlm.nih.gov/pubmed/28012260 http://dx.doi.org/10.1002/chem.201605911 |
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