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Human β‐defensin 3 increases the TLR9‐dependent response to bacterial DNA

Human β‐defensin 3 (hBD3) is a cationic antimicrobial peptide with potent bactericidal activity in vitro. HBD3 is produced in response to pathogen challenge and can modulate immune responses. The amplified recognition of self‐DNA by human plasmacytoid dendritic cells has been previously reported, bu...

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Detalles Bibliográficos
Autores principales: McGlasson, Sarah L., Semple, Fiona, MacPherson, Heather, Gray, Mohini, Davidson, Donald J., Dorin, Julia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412915/
https://www.ncbi.nlm.nih.gov/pubmed/28102569
http://dx.doi.org/10.1002/eji.201646799