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STAT3 promotes IFNγ/TNFα‐induced muscle wasting in an NF‐κB‐dependent and IL‐6‐independent manner

Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial nature of this syndrome and the implication of cytokines such as IL‐6, IFNγ, and TNFα is well established, we still do not know how various ef...

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Detalles Bibliográficos
Autores principales: Ma, Jennifer F, Sanchez, Brenda J, Hall, Derek T, Tremblay, Anne‐Marie K, Di Marco, Sergio, Gallouzi, Imed‐Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412921/
https://www.ncbi.nlm.nih.gov/pubmed/28264935
http://dx.doi.org/10.15252/emmm.201607052