Self-adjusting synthetic gene circuit for correcting insulin resistance

By using tools from synthetic biology, sophisticated genetic devices can be assembled to reprogram mammalian cell activities. Here, we demonstrate that a self-adjusting synthetic gene circuit can be designed to sense and reverse the insulin-resistance syndrome in different mouse models. By functiona...

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Detalles Bibliográficos
Autores principales: Ye, Haifeng, Xie, Mingqi, Xue, Shuai, Charpin-El Hamri, Ghislaine, Yin, Jianli, Zulewski, Henryk, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412959/
https://www.ncbi.nlm.nih.gov/pubmed/28480128
http://dx.doi.org/10.1038/s41551-016-0005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412959/
https://www.ncbi.nlm.nih.gov/pubmed/28480128
http://dx.doi.org/10.1038/s41551-016-0005

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