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Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis

The human papillomavirus type 16 (HPV16) L2 protein acts as a chaperone to ensure that the viral genome (vDNA) traffics from endosomes to the trans-Golgi network (TGN) and eventually the nucleus, where HPV replication occurs. En route to the nucleus, the L2/vDNA complex must translocate across limit...

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Detalles Bibliográficos
Autores principales: Calton, Christine M., Bronnimann, Matthew P., Manson, Ariana R., Li, Shuaizhi, Chapman, Janice A., Suarez-Berumen, Marcela, Williamson, Tatum R., Molugu, Sudheer K., Bernal, Ricardo A., Campos, Samuel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412990/
https://www.ncbi.nlm.nih.gov/pubmed/28463988
http://dx.doi.org/10.1371/journal.ppat.1006200