Radiochemistry on electrodes: Synthesis of an (18)F-labelled and in vivo stable COX-2 inhibitor

New radiochemistry techniques can yield novel PET tracers for COX-2 and address the shortcomings in in vivo stability and specificity, which have held back clinical translation of tracers to image COX-2 expression. Current techniques limit radiosynthesis to analogs of the COX-2 inhibitors with fluor...

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Detalles Bibliográficos
Autores principales: Lebedev, Artem, Jiao, Jing, Lee, Jason, Yang, Fan, Allison, Nathanael, Herschman, Harvey, Sadeghi, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413030/
https://www.ncbi.nlm.nih.gov/pubmed/28464017
http://dx.doi.org/10.1371/journal.pone.0176606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413030/
https://www.ncbi.nlm.nih.gov/pubmed/28464017
http://dx.doi.org/10.1371/journal.pone.0176606

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