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Radiochemistry on electrodes: Synthesis of an (18)F-labelled and in vivo stable COX-2 inhibitor
New radiochemistry techniques can yield novel PET tracers for COX-2 and address the shortcomings in in vivo stability and specificity, which have held back clinical translation of tracers to image COX-2 expression. Current techniques limit radiosynthesis to analogs of the COX-2 inhibitors with fluor...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413030/ https://www.ncbi.nlm.nih.gov/pubmed/28464017 http://dx.doi.org/10.1371/journal.pone.0176606 |