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Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS(+) circulating memory T follicular-helper cells which is impaired by HIV infection
Dysfunction of T follicular-helper (T(FH)) cells is a possible cause of impaired germinal centre (GC) and IgG antibody responses in individuals with human immunodeficiency virus-1 (HIV-1) infection and might contribute to decreased magnitude and isotype diversification of IgG antibodies to pneumococ...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413043/ https://www.ncbi.nlm.nih.gov/pubmed/28463977 http://dx.doi.org/10.1371/journal.pone.0176641 |