Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular mechanism responsible for fatty acid stimulation of TLR4 remains unknown. Here, we demonstrate that PA functions as a lig...

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Detalles Bibliográficos
Autores principales: Nicholas, Dequina A., Zhang, Kangling, Hung, Christopher, Glasgow, Shane, Aruni, Aruni Wilson, Unternaehrer, Juli, Payne, Kimberly J., Langridge, William H. R., De Leon, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413048/
https://www.ncbi.nlm.nih.gov/pubmed/28463985
http://dx.doi.org/10.1371/journal.pone.0176793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413048/
https://www.ncbi.nlm.nih.gov/pubmed/28463985
http://dx.doi.org/10.1371/journal.pone.0176793

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