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α-Klotho expression determines nitric oxide synthesis in response to FGF-23 in human aortic endothelial cells

Endothelial cells (ECs) express fibroblast growth factor (FGF) receptors and are metabolically active after treatment with FGF-23. It is not known if this effect is α-Klotho independent or mediated by humoral or endogenous endothelial α-Klotho. In the present study, we aimed to characterize EC α-Klo...

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Detalles Bibliográficos
Autores principales: Chung, Chih-Ping, Chang, Yu-Chun, Ding, Yan, Lim, Kenneth, Liu, Qinghua, Zhu, Langjing, Zhang, Wei, Lu, Tzong-Shi, Molostvov, Guerman, Zehnder, Daniel, Hsiao, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413063/
https://www.ncbi.nlm.nih.gov/pubmed/28463984
http://dx.doi.org/10.1371/journal.pone.0176817