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MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer

BACKGROUND: Mucin1 (MUC1), a glycoprotein associated with chemoresistance and an aggressive cancer phenotype, is aberrantly overexpressed in triple-negative breast cancer (TNBC). Recent studies suggest that MUC1 plays a role in modulating cancer cell metabolism and thereby supports tumor growth. Her...

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Detalles Bibliográficos
Autores principales: Goode, Gennifer, Gunda, Venugopal, Chaika, Nina V., Purohit, Vinee, Yu, Fang, Singh, Pankaj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413086/
https://www.ncbi.nlm.nih.gov/pubmed/28464016
http://dx.doi.org/10.1371/journal.pone.0176820