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Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome()
Alcohol use disorders are common both in the United States and globally, and are associated with a variety of co-morbid, inflammation-linked diseases. The pathogenesis of many of these ailments are driven by the activation of the NLRP3 inflammasome, a multi-protein intracellular pattern recognition...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413213/ https://www.ncbi.nlm.nih.gov/pubmed/28463821 http://dx.doi.org/10.1016/j.redox.2017.04.020 |