NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

Inflammation in the brain accompanies several high-impact neurological diseases including multiple sclerosis (MS), stroke, and Alzheimer’s disease. Neuroinflammation is sterile, as damage-associated molecular patterns rather than microbial pathogens elicit the response. The inflammasome, which leads...

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Detalles Bibliográficos
Autores principales: Freeman, Leslie, Guo, Haitao, David, Clément N., Brickey, W. June, Jha, Sushmita, Ting, Jenny P.-Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413320/
https://www.ncbi.nlm.nih.gov/pubmed/28404595
http://dx.doi.org/10.1084/jem.20150237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413320/
https://www.ncbi.nlm.nih.gov/pubmed/28404595
http://dx.doi.org/10.1084/jem.20150237

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