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In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein

Zoonotic transmission of influenza A viruses can give rise to devastating pandemics, but currently it is impossible to predict the pandemic potential of circulating avian influenza viruses. Here, we describe a new mouse model suitable for such risk assessment, based on the observation that the innat...

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Detalles Bibliográficos
Autores principales: Deeg, Christoph M., Hassan, Ebrahim, Mutz, Pascal, Rheinemann, Lara, Götz, Veronika, Magar, Linda, Schilling, Mirjam, Kallfass, Carsten, Nürnberger, Cindy, Soubies, Sébastien, Kochs, Georg, Haller, Otto, Schwemmle, Martin, Staeheli, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413327/
https://www.ncbi.nlm.nih.gov/pubmed/28396461
http://dx.doi.org/10.1084/jem.20161033