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BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection

Inappropriate IL-17 responses are implicated in chronic tissue inflammation. IL-23 contributes to Trypanosoma cruzi–specific IL-17 production, but the molecular mechanisms underlying regulation of the IL-23–IL-17 axis during T. cruzi infection are poorly understood. Here, we demonstrate a novel func...

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Detalles Bibliográficos
Autores principales: Kitada, Shoko, Kayama, Hisako, Okuzaki, Daisuke, Koga, Ritsuko, Kobayashi, Masao, Arima, Yasunobu, Kumanogoh, Atsushi, Murakami, Masaaki, Ikawa, Masahito, Takeda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413328/
https://www.ncbi.nlm.nih.gov/pubmed/28356392
http://dx.doi.org/10.1084/jem.20161076