Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs

TLR7/9 signals are capable of mounting massive interferon (IFN) response in plasmacytoid dendritic cells (pDCs) immediately after viral infection, yet the involvement of epigenetic regulation in this process has not been documented. Here, we report that zinc finger CXXC family epigenetic regulator C...

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Detalles Bibliográficos
Autores principales: Ma, Shixin, Wan, Xiaoling, Deng, Zihou, Shi, Lei, Hao, Congfang, Zhou, Zhenyuan, Zhou, Chun, Fang, Yiyuan, Liu, Jinghua, Yang, Jing, Chen, Xia, Li, Tiantian, Zang, Aiping, Yin, Shigang, Li, Bin, Plumas, Joel, Chaperot, Laurence, Zhang, Xiaoming, Xu, Guoliang, Jiang, Lubin, Shen, Nan, Xiong, Sidong, Gao, Xiaoming, Zhang, Yan, Xiao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413332/
https://www.ncbi.nlm.nih.gov/pubmed/28416650
http://dx.doi.org/10.1084/jem.20161149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413332/
https://www.ncbi.nlm.nih.gov/pubmed/28416650
http://dx.doi.org/10.1084/jem.20161149

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