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Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior

Abnormal epigenetic regulation can cause the nervous system to develop abnormally. Here, we sought to understand the mechanism by which this occurs by investigating the protein complex cohesin, which is considered to regulate gene expression and, when defective, is associated with higher-level brain...

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Detalles Bibliográficos
Autores principales: Fujita, Yuki, Masuda, Koji, Bando, Masashige, Nakato, Ryuichiro, Katou, Yuki, Tanaka, Takashi, Nakayama, Masahiro, Takao, Keizo, Miyakawa, Tsuyoshi, Tanaka, Tatsunori, Ago, Yukio, Hashimoto, Hitoshi, Shirahige, Katsuhiko, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413336/
https://www.ncbi.nlm.nih.gov/pubmed/28408410
http://dx.doi.org/10.1084/jem.20161517