Cargando…
Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior
Abnormal epigenetic regulation can cause the nervous system to develop abnormally. Here, we sought to understand the mechanism by which this occurs by investigating the protein complex cohesin, which is considered to regulate gene expression and, when defective, is associated with higher-level brain...
Autores principales: | Fujita, Yuki, Masuda, Koji, Bando, Masashige, Nakato, Ryuichiro, Katou, Yuki, Tanaka, Takashi, Nakayama, Masahiro, Takao, Keizo, Miyakawa, Tsuyoshi, Tanaka, Tatsunori, Ago, Yukio, Hashimoto, Hitoshi, Shirahige, Katsuhiko, Yamashita, Toshihide |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413336/ https://www.ncbi.nlm.nih.gov/pubmed/28408410 http://dx.doi.org/10.1084/jem.20161517 |
Ejemplares similares
-
Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation
por: Wang, Jiankang, et al.
Publicado: (2022) -
Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors
por: Nakato, Ryuichiro, et al.
Publicado: (2023) -
Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation
por: Kubota, Takashi, et al.
Publicado: (2015) -
Displacement and re-accumulation of centromeric cohesin during transient pre-anaphase centromere splitting
por: Ocampo-Hafalla, Maria T., et al.
Publicado: (2007) -
Cohesin-dependent chromosome loop extrusion is limited by transcription and stalled replication forks
por: Jeppsson, Kristian, et al.
Publicado: (2022)