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Lissencephaly-1 is a context-dependent regulator of the human dynein complex

The cytoplasmic dynein-1 (dynein) motor plays a central role in microtubule organisation and cargo transport. These functions are spatially regulated by association of dynein and its accessory complex dynactin with dynamic microtubule plus ends. Here, we elucidate in vitro the roles of dynactin, end...

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Detalles Bibliográficos
Autores principales: Baumbach, Janina, Murthy, Andal, McClintock, Mark A, Dix, Carly I, Zalyte, Ruta, Hoang, Ha Thi, Bullock, Simon L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413349/
https://www.ncbi.nlm.nih.gov/pubmed/28406398
http://dx.doi.org/10.7554/eLife.21768