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TRPV1 Activation Counters Diet-Induced Obesity Through Sirtuin-1 activation and PRDM-16 Deacetylation in Brown Adipose Tissue

BACKGROUND/OBJECTIVE: An imbalance between energy intake and expenditure leads to obesity. Increasing metabolism and thermogenesis in brown adipose tissue (BAT) can help in overcoming obesity. Here, we investigated the effect of activation of transient receptor potential vanilloid subfamily 1 (TRPV1...

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Detalles Bibliográficos
Autores principales: Baskaran, Padmamalini, Krishnan, Vivek, Fettel, Kevin, Gao, Peng, Zhu, Zhiming, Ren, Jun, Thyagarajan, Baskaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413365/
https://www.ncbi.nlm.nih.gov/pubmed/28104916
http://dx.doi.org/10.1038/ijo.2017.16