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Endoplasmic Reticulum–Mitochondrial Ca(2+) Fluxes Underlying Cancer Cell Survival

Calcium ions (Ca(2+)) are crucial, ubiquitous, intracellular second messengers required for functional mitochondrial metabolism during uncontrolled proliferation of cancer cells. The mitochondria and the endoplasmic reticulum (ER) are connected via “mitochondria-associated ER membranes” (MAMs) where...

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Detalles Bibliográficos
Autores principales: Ivanova, Hristina, Kerkhofs, Martijn, La Rovere, Rita M., Bultynck, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413502/
https://www.ncbi.nlm.nih.gov/pubmed/28516062
http://dx.doi.org/10.3389/fonc.2017.00070