NF-κB Immunity in the Brain Determines Fly Lifespan in Healthy Aging and Age-Related Neurodegeneration

During aging, innate immunity progresses to a chronically active state. However, what distinguishes those that “age well” from those developing age-related neurological conditions is unclear. We used Drosophila to explore the cost of immunity in the aging brain. We show that mutations in intracellul...

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Detalles Bibliográficos
Autores principales: Kounatidis, Ilias, Chtarbanova, Stanislava, Cao, Yang, Hayne, Margaret, Jayanth, Dhruv, Ganetzky, Barry, Ligoxygakis, Petros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413584/
https://www.ncbi.nlm.nih.gov/pubmed/28445733
http://dx.doi.org/10.1016/j.celrep.2017.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413584/
https://www.ncbi.nlm.nih.gov/pubmed/28445733
http://dx.doi.org/10.1016/j.celrep.2017.04.007

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