An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) are an important system to study early human development, model human diseases, and develop cell replacement therapies. However, genetic manipulation of hPSCs is challenging and a method to simultaneously activate multiple genomic sites in a controllable manner i...

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Detalles Bibliográficos
Autores principales: Guo, Jianying, Ma, Dacheng, Huang, Rujin, Ming, Jia, Ye, Min, Kee, Kehkooi, Xie, Zhen, Na, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413595/
https://www.ncbi.nlm.nih.gov/pubmed/28116670
http://dx.doi.org/10.1007/s13238-016-0360-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413595/
https://www.ncbi.nlm.nih.gov/pubmed/28116670
http://dx.doi.org/10.1007/s13238-016-0360-8

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