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Chemical synthesis of long RNAs with terminal 5′‐phosphate groups

Long structured RNAs are useful biochemical and biological tools. They are usually prepared enzymatically, but this precludes their site‐specific modification with functional groups for chemical biology studies. One solution is to perform solid‐phase synthesis of multiple RNAs loaded with 5′‐termina...

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Detalles Bibliográficos
Autores principales: Pradère, Ugo, Halloy, François, Hall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413853/
https://www.ncbi.nlm.nih.gov/pubmed/28295757
http://dx.doi.org/10.1002/chem.201700514