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Stem cell proliferation patterns as an alternative for in vivo prediction and discrimination of carcinogenic compounds

One of the major challenges in the development of alternative carcinogenicity assays is the prediction of non-genotoxic carcinogens. The variety of non-genotoxic cancer pathways complicates the search for reliable parameters expressing their carcinogenicity. As non-genotoxic and genotoxic carcinogen...

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Detalles Bibliográficos
Autores principales: Stevens, An-Sofie, Willems, Maxime, Plusquin, Michelle, Ploem, Jan-Pieter, Winckelmans, Ellen, Artois, Tom, Smeets, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413882/
https://www.ncbi.nlm.nih.gov/pubmed/28466856
http://dx.doi.org/10.1038/srep45616