Cargando…

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Homology and similarity based approaches are most widely used for the identification of new enzymes for biocatalysis. However, they are not suitable to find truly novel scaffolds with a desired function and this averts options and diversity. Hydroxynitrile lyases (HNLs) are an example of non-homolog...

Descripción completa

Detalles Bibliográficos
Autores principales: Lanfranchi, Elisa, Pavkov-Keller, Tea, Koehler, Eva-Maria, Diepold, Matthias, Steiner, Kerstin, Darnhofer, Barbara, Hartler, Jürgen, Van Den Bergh, Tom, Joosten, Henk-Jan, Gruber-Khadjawi, Mandana, Thallinger, Gerhard G., Birner-Gruenberger, Ruth, Gruber, Karl, Winkler, Margit, Glieder, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413884/
https://www.ncbi.nlm.nih.gov/pubmed/28466867
http://dx.doi.org/10.1038/srep46738