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Posttreatment with Protectin DX ameliorates bleomycin-induced pulmonary fibrosis and lung dysfunction in mice

Protectin DX (10S,17S-dihydroxydocosa-4Z,7Z,11E,13Z,15E,19Z-hexaenoic acid) (PDX), generated from Ω-3 fatty docosahexaenoic acids, is believed to exert anti-inflammatory and proresolution bioactions. To date, few studies have been performed regarding its effect on pulmonary fibrosis. Herein we show...

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Detalles Bibliográficos
Autores principales: Li, Hui, Hao, Yu, Zhang, Huawei, Ying, Weiyang, Li, Dan, Ge, Yahe, Ying, Binyu, Cheng, Bihuan, Lian, Qingquan, Jin, Shengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413938/
https://www.ncbi.nlm.nih.gov/pubmed/28466866
http://dx.doi.org/10.1038/srep46754