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A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue
To date, reprogramming strategies for generating cell types of interest have been facilitated by detailed understanding of relevant developmental regulatory factors. However, identification of such regulatory drivers often represents a major challenge, as specific gene combinations may be required f...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413950/ https://www.ncbi.nlm.nih.gov/pubmed/28429718 http://dx.doi.org/10.1038/ncomms14662 |