LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

We have previously shown that lipoma preferred partner (LPP) mediates TGFβ-induced breast cancer cell migration and invasion. Herein, we demonstrate that diminished LPP expression reduces circulating tumour cell numbers, impairs cancer cell extravasation and diminishes lung metastasis. LPP localizes...

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Detalles Bibliográficos
Autores principales: Ngan, Elaine, Stoletov, Konstantin, Smith, Harvey W., Common, Jessica, Muller, William J., Lewis, John D., Siegel, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413977/
https://www.ncbi.nlm.nih.gov/pubmed/28436416
http://dx.doi.org/10.1038/ncomms15059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413977/
https://www.ncbi.nlm.nih.gov/pubmed/28436416
http://dx.doi.org/10.1038/ncomms15059

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