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Structure and function of the divalent anion/Na(+) symporter from Vibrio cholerae and a humanized variant

Integral membrane proteins of the divalent anion/Na(+) symporter (DASS) family translocate dicarboxylate, tricarboxylate or sulphate across cell membranes, typically by utilizing the preexisting Na(+) gradient. The molecular determinants for substrate recognition by DASS remain obscure, largely owin...

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Detalles Bibliográficos
Autores principales: Nie, Rongxin, Stark, Steven, Symersky, Jindrich, Kaplan, Ronald S., Lu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413979/
https://www.ncbi.nlm.nih.gov/pubmed/28436435
http://dx.doi.org/10.1038/ncomms15009