Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations

Although numerous genetic studies have been conducted for bipolar disorder (BD), its genetic architecture remains elusive. Here we perform, to the best of our knowledge, the first trio-based exome sequencing study for BD to investigate potential roles of de novo mutations in the disease etiology. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Kataoka, M, Matoba, N, Sawada, T, Kazuno, A-A, Ishiwata, M, Fujii, K, Matsuo, K, Takata, A, Kato, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414074/
https://www.ncbi.nlm.nih.gov/pubmed/27217147
http://dx.doi.org/10.1038/mp.2016.69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414074/
https://www.ncbi.nlm.nih.gov/pubmed/27217147
http://dx.doi.org/10.1038/mp.2016.69

Ejemplares similares