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Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations
Although numerous genetic studies have been conducted for bipolar disorder (BD), its genetic architecture remains elusive. Here we perform, to the best of our knowledge, the first trio-based exome sequencing study for BD to investigate potential roles of de novo mutations in the disease etiology. We...
Autores principales: | Kataoka, M, Matoba, N, Sawada, T, Kazuno, A-A, Ishiwata, M, Fujii, K, Matsuo, K, Takata, A, Kato, T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414074/ https://www.ncbi.nlm.nih.gov/pubmed/27217147 http://dx.doi.org/10.1038/mp.2016.69 |
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