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Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia

BACKGROUND: Neutrophils produce and carry key components of the alternative pathway (AP) of complement, including properdin (P). The effect of chemotherapy-induced absolute neutropenia on circulating P levels and AP function has not been previously established. METHODS: We prospectively measured fre...

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Detalles Bibliográficos
Autores principales: Tsyrkunou, Artsiom, Agarwal, Sarika, Koirala, Bibek, Finberg, Robert W., Nath, Rajneesh, Barton, Bruce, Levitz, Stuart M., Wang, Jennifer P., Ram, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414105/
https://www.ncbi.nlm.nih.gov/pubmed/28480246
http://dx.doi.org/10.1093/ofid/ofw250