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Development of a core Clostridium thermocellum kinetic metabolic model consistent with multiple genetic perturbations

BACKGROUND: Clostridium thermocellum is a Gram-positive anaerobe with the ability to hydrolyze and metabolize cellulose into biofuels such as ethanol, making it an attractive candidate for consolidated bioprocessing (CBP). At present, metabolic engineering in C. thermocellum is hindered due to the i...

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Detalles Bibliográficos
Autores principales: Dash, Satyakam, Khodayari, Ali, Zhou, Jilai, Holwerda, Evert K., Olson, Daniel G., Lynd, Lee R., Maranas, Costas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414155/
https://www.ncbi.nlm.nih.gov/pubmed/28469704
http://dx.doi.org/10.1186/s13068-017-0792-2