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Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers

BACKGROUND: Early diagnosis of rheumatoid arthritis (RA) is crucial to providing effective therapy and often hampered by unspecific clinical manifestations. Elevated levels of extracellular circulating DNA (cirDNA) in patients with autoimmune disease were found to be associated with etiopathogenesis...

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Detalles Bibliográficos
Autores principales: Rykova, Elena, Sizikov, Aleksey, Roggenbuck, Dirk, Antonenko, Oksana, Bryzgalov, Leonid, Morozkin, Evgeniy, Skvortsova, Kseniya, Vlassov, Valentin, Laktionov, Pavel, Kozlov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414163/
https://www.ncbi.nlm.nih.gov/pubmed/28464939
http://dx.doi.org/10.1186/s13075-017-1295-z