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Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

BACKGROUND: Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a recent increase in incidence in many countries. Although PTC has been explored by gene expression and DNA methylation studies, the regulatory mechanisms of the methylation on the gene expression was poorly clarified....

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Detalles Bibliográficos
Autores principales: Beltrami, Caroline Moraes, dos Reis, Mariana Bisarro, Barros-Filho, Mateus Camargo, Marchi, Fabio Albuquerque, Kuasne, Hellen, Pinto, Clóvis Antônio Lopes, Ambatipudi, Srikant, Herceg, Zdenko, Kowalski, Luiz Paulo, Rogatto, Silvia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414166/
https://www.ncbi.nlm.nih.gov/pubmed/28469731
http://dx.doi.org/10.1186/s13148-017-0346-2