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Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

The exact nature and dynamics of pancreatic ductal adenocarcinoma (PDAC) immune composition remains largely unknown. Desmoplasia is suggested to polarize PDAC immunity. Therefore, a comprehensive evaluation of the composition and distribution of desmoplastic elements and T-cell infiltration is neces...

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Detalles Bibliográficos
Autores principales: Carstens, Julienne L., Correa de Sampaio, Pedro, Yang, Dalu, Barua, Souptik, Wang, Huamin, Rao, Arvind, Allison, James P., LeBleu, Valerie S., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414182/
https://www.ncbi.nlm.nih.gov/pubmed/28447602
http://dx.doi.org/10.1038/ncomms15095