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Inferring the physical properties of yeast chromatin through Bayesian analysis of whole nucleus simulations
BACKGROUND: The structure and mechanical properties of chromatin impact DNA functions and nuclear architecture but remain poorly understood. In budding yeast, a simple polymer model with minimal sequence-specific constraints and a small number of structural parameters can explain diverse experimenta...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414205/ https://www.ncbi.nlm.nih.gov/pubmed/28468672 http://dx.doi.org/10.1186/s13059-017-1199-x |