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Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts

BACKGROUND: Malignant pleural mesothelioma (MPM) is a difficult-to-treat global disease. Pegylated arginase (BCT-100) has recently shown anti-tumor effects in hepatocellular carcinoma, acute myeloid leukemia and melanoma. This study aims to investigate the effects of PEG-BCT-100 in MPM. METHODS: A p...

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Detalles Bibliográficos
Autores principales: Lam, Sze-Kwan, Li, Yuan-Yuan, Xu, Shi, Leung, Leanne Lee, U, Kin-Pong, Zheng, Yan-Fang, Cheng, Paul Ning-Man, Ho, James Chung-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414232/
https://www.ncbi.nlm.nih.gov/pubmed/28464918
http://dx.doi.org/10.1186/s12931-017-0564-3