Ordinary differential equations and Boolean networks in application to modelling of 6-mercaptopurine metabolism

We consider two approaches to modelling the cell metabolism of 6-mercaptopurine, one of the important chemotherapy drugs used for treating acute lymphocytic leukaemia: kinetic ordinary differential equations, and Boolean networks supplied with one controlling node, which takes continual values. We a...

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Detalles Bibliográficos
Autores principales: Lavrova, Anastasia I., Postnikov, Eugene B., Zyubin, Andrey Yu., Babak, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Biochemistry and Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414245/
https://www.ncbi.nlm.nih.gov/pubmed/28484608
http://dx.doi.org/10.1098/rsos.160872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414245/
https://www.ncbi.nlm.nih.gov/pubmed/28484608
http://dx.doi.org/10.1098/rsos.160872

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