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Ordinary differential equations and Boolean networks in application to modelling of 6-mercaptopurine metabolism
We consider two approaches to modelling the cell metabolism of 6-mercaptopurine, one of the important chemotherapy drugs used for treating acute lymphocytic leukaemia: kinetic ordinary differential equations, and Boolean networks supplied with one controlling node, which takes continual values. We a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society Publishing
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414245/ https://www.ncbi.nlm.nih.gov/pubmed/28484608 http://dx.doi.org/10.1098/rsos.160872 |