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The development of bispecific antibodies and their applications in tumor immune escape

During the past two decades, a great evolution of bispecific antibodies (BsAbs) for therapeutic applications has been made. BsAbs can bind simultaneously two different antigens or epitopes, which leads to a wide range of applications including redirecting T cells or NK cells to tumor cells, blocking...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolong, Yang, Yuanyuan, Fan, Dongmei, Xiong, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414286/
https://www.ncbi.nlm.nih.gov/pubmed/28469973
http://dx.doi.org/10.1186/s40164-017-0072-7