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FBXW7 expression is associated with prognosis and chemotherapeutic outcome in Chinese patients with gastric adenocarcinoma

BACKGROUND: FBXW7, a component of the Skp-Cullin1-F-box, mediates target protein recognition. It is a tumor suppressor gene that plays a role in the regulation of cell cycle exit and reentry via c-Myc, c-Jun and Notch degradation. There are few studies, particularly involving a large patient cohort,...

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Detalles Bibliográficos
Autores principales: Li, Mao-Ran, Zhu, Chun-Chao, Ling, Tian-Long, Zhang, Ye-Qian, Xu, Jia, Zhao, En-Hao, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414332/
https://www.ncbi.nlm.nih.gov/pubmed/28464881
http://dx.doi.org/10.1186/s12876-017-0616-7