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Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers

BACKGROUND: Ongoing intra-host HIV-1 evolution has been shown in individuals that naturally suppress the viremia to low levels (HIV controllers) by the analysis of the RNA in plasma compartment. Detection of evolution at the DNA proviral compartment in HIV controllers, however, has been more challen...

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Detalles Bibliográficos
Autores principales: de Azevedo, Suwellen S. D., Caetano, Diogo Gama, Côrtes, Fernanda H., Teixeira, Sylvia L. M., dos Santos Silva, Karina, Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea G., Morgado, Mariza G., Bello, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414336/
https://www.ncbi.nlm.nih.gov/pubmed/28464889
http://dx.doi.org/10.1186/s12977-017-0354-5