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Trk Receptors and Neurotrophin Cross-Interactions: New Perspectives Toward Manipulating Therapeutic Side-Effects

Some therapeutic side-effects result from simultaneous activation of homolog receptors by the same ligand. Tropomyosin receptor kinases (TrkA, TrkB and TrkC) play a major role in the development and biology of neurons through neurotrophin signaling. The wide range of cross-interactions between Trk r...

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Detalles Bibliográficos
Autores principales: Haddad, Yazan, Adam, Vojtěch, Heger, Zbyněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414483/
https://www.ncbi.nlm.nih.gov/pubmed/28515680
http://dx.doi.org/10.3389/fnmol.2017.00130