Febuxostat Attenuates Renal Damage besides Exerting Hypouricemic Effect in Streptozotocin-Induced Diabetic Rats

Aim. In this study, we aimed to investigate the effects of febuxostat, a novel inhibitor of xanthine oxidase (XO), on renal damage in streptozotocin- (STZ-) induced diabetic rats. Methods. Diabetes was induced by the intraperitoneal injection of STZ in male Sprague-Dawley rats. Sham-injected rats se...

Descripción completa

Detalles Bibliográficos
Autores principales: Ran, Jianmin, Xu, Gang, Ma, Huixuan, Xu, Hailing, Liu, Yan, Tan, Rongshao, Zhu, Ping, Song, Jun, Lao, Gancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414495/
https://www.ncbi.nlm.nih.gov/pubmed/28503330
http://dx.doi.org/10.1155/2017/2739539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414495/
https://www.ncbi.nlm.nih.gov/pubmed/28503330
http://dx.doi.org/10.1155/2017/2739539

Ejemplares similares