Cargando…

Febuxostat Attenuates Renal Damage besides Exerting Hypouricemic Effect in Streptozotocin-Induced Diabetic Rats

Aim. In this study, we aimed to investigate the effects of febuxostat, a novel inhibitor of xanthine oxidase (XO), on renal damage in streptozotocin- (STZ-) induced diabetic rats. Methods. Diabetes was induced by the intraperitoneal injection of STZ in male Sprague-Dawley rats. Sham-injected rats se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ran, Jianmin, Xu, Gang, Ma, Huixuan, Xu, Hailing, Liu, Yan, Tan, Rongshao, Zhu, Ping, Song, Jun, Lao, Gancheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414495/ https://www.ncbi.nlm.nih.gov/pubmed/28503330 http://dx.doi.org/10.1155/2017/2739539

Ejemplares similares

Low Protein Diet Inhibits Uric Acid Synthesis and Attenuates Renal Damage in Streptozotocin-Induced Diabetic Rats
por: Ran, Jianmin, et al.
Publicado: (2014)

Hypouricemic effect and safety of febuxostat used for prevention of tumor lysis syndrome
por: Maie, Koichiro, et al.
Publicado: (2014)

Lack of xanthine dehydrogenase leads to a remarkable renal decline in a novel hypouricemic rat model
por: Dissanayake, Lashodya V., et al.
Publicado: (2022)

The Hypouricemic Effect of Balanophora laxiflora Extracts and Derived Phytochemicals in Hyperuricemic Mice
por: Ho, Shang-Tse, et al.
Publicado: (2012)

PEP, and more besides...
Publicado: (1980)

Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2
por: Taniguchi, Tetsuya, et al.
Publicado: (2021)

Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
por: Nomura, Johji, et al.
Publicado: (2014)

Biopharmaceutical Study on Nobiletin-Loaded Amorphous Solid Dispersion with Improved Hypouricemic Effect
por: Nihei, Takuya, et al.
Publicado: (2021)

Beside the bonnie brier bush
por: Maclaren, Ian, 1850-1907
Publicado: (1890)

Hypouricemic Effects of Chrysanthemum indicum L. and Cornus officinalis on Hyperuricemia-Induced HepG2 Cells, Renal Cells, and Mice
por: Kim, Ok-Kyung, et al.
Publicado: (2021)

Replacing of sedentary behavior with physical activity and the risk of mortality in people with prediabetes and diabetes: a prospective cohort study
por: Zhu, Ping, et al.
Publicado: (2023)

Hypouricemic Effects of Ganoderma applanatum in Hyperuricemia Mice through OAT1 and GLUT9
por: Yong, Tianqiao, et al.
Publicado: (2018)

Hypouricemic Effect of Submerged Culture of Ganoderma lucidum in Potassium Oxonate-Induced Hyperuricemic Rats
por: Huang, Chung-Hsiung, et al.
Publicado: (2022)

Febuxostat methanol solvate
por: Jiang, Qi-Ying, et al.
Publicado: (2011)

Febuxostat ethanol monosolvate
por: Gelbrich, Thomas, et al.
Publicado: (2020)

Successful febuxostat desensitization in a patient with febuxostat hypersensitivity: A Malaysian experience
por: Sulaiman, Narisa, et al.
Publicado: (2017)

Glioblastoma Treatment Modalities besides Surgery
por: Zhang, Hao, et al.
Publicado: (2019)

Evaluation of Xanthine Oxidase Inhibitory Potential and In vivo Hypouricemic Activity of Dimocarpus longan Lour. Extracts
por: Sheu, Shi-Yuan, et al.
Publicado: (2016)

Hypouricemic Effect of Ethanol Extract of Aster glehni Leaves in Potassium Oxonate-Induced Hyperuricemic Rats
por: Park, Ji-Eun, et al.
Publicado: (2018)

Anti-Inflammatory and Hypouricemic Effect of Bioactive Compounds: Molecular Evidence and Potential Application in the Management of Gout
por: Scanu, Anna, et al.
Publicado: (2022)

Febuxostat pretreatment attenuates myocardial ischemia/reperfusion injury via mitochondrial apoptosis
por: Wang, Shulin, et al.
Publicado: (2015)

SAT-079 Renal Protective Effects Of Topiroxostat And Febuxostat In Hypertensives With Hyperuricemia.
por: Satoh, Fumitoshi, et al.
Publicado: (2019)

Genistein attenuates renal fibrosis in streptozotocin-induced diabetic rats
por: Jia, Qiang, et al.
Publicado: (2019)

Febuxostat and the Black Box Blues
por: Abeles, Aryeh M., et al.
Publicado: (2019)

Improved biological properties and hypouricemic effects of uricase from Candida utilis loaded in novel alkaline enzymosomes
por: Tan, Qun-You, et al.
Publicado: (2012)

Hypouricemic Effects of Extracts From Agrocybe aegerita on Hyperuricemia Mice and Virtual Prediction of Bioactives by Molecular Docking
por: Yong, Tianqiao, et al.
Publicado: (2018)

In vitro and in vivo evidence of hypouricemic and anti-inflammatory activities of Maclura cochinchinensis (Lour.) Corner heartwood extract
por: Sato, Vilasinee H., et al.
Publicado: (2019)

Besides Symptoms: Unheard Narratives in Research on Schizophrenia
por: Mehrotra, Seema, et al.
Publicado: (2013)

Other clinical applications of videolaryngoscopy besides intubation
por: Shamim, Faisal, et al.
Publicado: (2018)

Treatment of Functional Hypogonadism Besides Pharmacological Substitution
por: Corona, Giovanni, et al.
Publicado: (2020)

Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Pharmacokinetics and pharmacodynamics of febuxostat under fasting conditions in healthy individuals
por: ZHANG, MEI, et al.
Publicado: (2014)

Melatonin and/or rowatinex attenuate streptozotocin-induced diabetic renal injury in rats
por: Motawi, Tarek K, et al.
Publicado: (2019)

Pentoxifylline Diminishes the Oxidative Damage to Renal Tissue Induced by Streptozotocin in the Rat
por: Dávila-Esqueda, M. E., et al.
Publicado: (2004)

Evaluation of the Usefulness of Topological Indices for Predicting Selected Physicochemical Properties of Bioactive Substances with Anti-Androgenic and Hypouricemic Activity
por: Wardecki, Dawid, et al.
Publicado: (2023)

Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy
por: He, Li, et al.
Publicado: (2017)

Management of hyperuricemia in gout: focus on febuxostat
por: Reinders, Mattheus K, et al.
Publicado: (2010)

Angiotensin(1–7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade
por: Zhang, Kai, et al.
Publicado: (2015)

Renal histopathological lesions after liver transplantation: What can we find besides calcineurin inhibitor-induced nephrotoxicity?
por: Jin, Haijiao, et al.
Publicado: (2022)

Clinician-performed Beside Ultrasound for the Diagnosis of Traumatic Pneumothorax
por: Ku, Bon S., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_dl0bqgtgjsubbiv181bi8cg0mj