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Methodological assessment of the reduction of the content of impurities in nimodipine emulsion via the use of 21 amino acid protection

PURPOSE: The present study examined the factors affecting the content of impurities of nimodipine (NMP) emulsion and the associated methods of compound protection. METHODS: Destructive testing of NMP emulsion and its active pharmaceutical ingredient (API) were conducted, and ultracentrifugation was...

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Detalles Bibliográficos
Autores principales: Xie, Yiqiao, Zhuang, Zhiquan, Zhang, Shu, Xia, Zihua, Chen, De, Fan, Kaiyan, Ren, Jialin, Lin, CuiCui, Chen, Yanzhong, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414723/
https://www.ncbi.nlm.nih.gov/pubmed/28490879
http://dx.doi.org/10.2147/IJN.S130348