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Methodological assessment of the reduction of the content of impurities in nimodipine emulsion via the use of 21 amino acid protection
PURPOSE: The present study examined the factors affecting the content of impurities of nimodipine (NMP) emulsion and the associated methods of compound protection. METHODS: Destructive testing of NMP emulsion and its active pharmaceutical ingredient (API) were conducted, and ultracentrifugation was...
Autores principales: | Xie, Yiqiao, Zhuang, Zhiquan, Zhang, Shu, Xia, Zihua, Chen, De, Fan, Kaiyan, Ren, Jialin, Lin, CuiCui, Chen, Yanzhong, Yang, Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414723/ https://www.ncbi.nlm.nih.gov/pubmed/28490879 http://dx.doi.org/10.2147/IJN.S130348 |
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